Resources

Welcome to our searchable resource and literature collection on safer supply and related topics.

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Ongoing law enforcement strategies to disrupt local unregulated drug markets can have an iatrogenic effect of increasing overdose by driving consumers towards new suppliers with unpredictable drug

Original research | 2025
Advocacy, Barriers and enablers, Decriminalization/legalization, Equity, Harm reduction, Illegal drugs, Legal system/law enforcement, Mortality, Overdose, Poverty

This study assesses the prevalence and correlates of chronic pain among primary fentanyl users.

Original research | 2024
Advocacy, About PWUD, Barriers and enablers, Chronic pain, Illegal drugs, Opioids, Substitution/OAT

A growing body of research details the impacts of COVID-19 pandemic-related public health directives and service disruptions on people who use unregulated drugs, however, there is limited research

Original research | 2025
About PWUD, Barriers and enablers, Equity, Illegal drugs, Harm reduction, Legal system/law enforcement, Overdose, Parents/caregivers, Sex/Gender , Stigma

This paper discusses the unique risk profile of potent, synthetic illegal drugs being packaged as counterfeit pills (as opposed to powder) in the context of overdose crises like those seen in North

Perspective | 2025
Illegal drugs, Diversion, Drug checking, Harm reduction, Overdose, Safer supply, Stigma, Substitution/OAT

People exposed to fentanyl may report that the dose of methadone in the commonly accepted therapeutic range feels too low. This paper examines self-reported methadone dose adequacy.

Original research | 2025
Advocacy, About PWUD, Illegal drugs, Opioids, Peer/PWLLE program involvement, Substitution/OAT, Withdrawal

This study examines the recent proliferation of manslaughter charges and subsequent prosecutions brought against people who have shared, sold, or provided drugs that have led to overdose death in C

Original research | 2024
Advocacy, About people who sell drugs, About PWUD, Decriminalization/legalization, Crime, Legal system/law enforcement, Policy/Regulatory, Overdose
Report | 2025
Benzodiazepines, Drug checking, Illegal drugs, Opioids, Overdose, Stimulants, Xylazine
Guidelines | 2024
About prescribers, Chronic pain, Clinical guidance, Mental health, Opioids, Overdose

Summarizes the Timmins Summit, held in partnership with the City of Timmins.

Report | 2024
Barriers and enablers, Housing, Illegal drugs, Legal system/law enforcement, Overdose, Policy/Regulatory, Small/medium cities, Stigma, Treatment/recovery

This paper describes the results of retrospective Safer Stimulant Supply program medical chart reviews.

Original research | 2025
Advocacy, Harm reduction, Housing, Illegal drugs, Injecting drugs, Safer supply, Social benefits, Stimulants, Wrap-around services

CCENDU, co-ordinated by the CCSA, publishes this newsletter regularly to inform people living in Canada about emerging substance use issues and trends.

Newsletter | 2025
Benzodiazepines, Drug checking, Harm reduction, Illegal drugs, Overdose, Withdrawal, Substitution/OAT

This toolkit emerges from a series of virtual Community Conversations that the Drug Policy Alliance co-hosted in 2021 with key community partners: Michigan Users Union, New England Users Union, Nat

Toolkit | 2024
Advocacy, About PWUD, Decriminalization/legalization, Harm reduction, Illegal drugs, Legal system/law enforcement, Overdose, Peer/PWLLE program involvement, Policy/Regulatory, Safer supply

This is a practice brief specific to AVI Health & Community Services prescribed alternatives program and service model in British Columbia.

Brief | 2025
Advocacy, Barriers and enablers, Harm reduction, Opioids, Overdose, Policy/Regulatory, Safer supply, Stigma, Stimulants, Substitution/OAT, Wrap-around services
Commentary | 2024
About people who use drugs, Advocacy, Barriers and enablers, Harm reduction, Illegal drugs, Legal system/law enforcement, Mortality, Overdose

We aimed to describe buprenorphine injection intended for sublingual use by rural people who inject drugs to inform patient-clinician discussions and public health in

Original research | 2024
About PWUD, Barriers and enablers, Illegal drugs, Injecting drugs, Opioids, Rural/remote, Substitution/OAT

Concerns around excessive opioid prescribing have been used to argue against the expansion of the scope of practice of nurse practitioners (NPs), but the association of NP practice independence wit

Original research | 2024
About prescribers, Opioids

This commentary explores a recent shift in British Columbia's drug policy under a novel drug “decriminalization” framework in the context of a severe crisis of drug-related overdoses and poisonings

Commentary | 2025
Advocacy, Crime, Decriminalization/legalization, Illegal drugs, Legal system/law enforcement, Overdose, Policy/Regulatory

The emergence of xylazine into the U.S. drug supply has increased demand for wound care services among people who inject drugs (PWID).

Original research | 2025
Barriers and enablers, Harm reduction, Illegal drugs, Injecting drugs, Policy/Regulatory, Wrap-around services

This study aimed to determine the prevalence of non-substance use-related mental health emergency department (ED) visits, hospitalizations, and outpatient physician visits for individuals receiving

Original research | 2025
Hospitals, Mental health, Opioids, Substitution/OAT

To examine neuroanatomical features associated with early substance use initiation and to what extent associations may reflect preexisting vulnerability.

Original research | 2024
About PWUD, Alcohol, Cannabis, Illegal drugs, Youth

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