Original research
by
Young, Samantha et al
Release Date
2025
Geography
Canada
Language of Resource
English
Full Text Available
No
Open Access / OK to Reproduce
No
Peer Reviewed
Yes
Objective
People exposed to fentanyl may report that the dose of methadone in the commonly accepted therapeutic range feels too low. This paper examines self-reported methadone dose adequacy.
Findings/Key points
The analysis demonstrates that exposure to non-fentanyl opioids while on methadone was not associated with feeling the dose was too low compared with individuals exposed to fentanyl. Our findings support adequate titration of methadone for individuals with continued exposure to unregulated opioids including fentanyl.
Design/methods
A retrospective cohort study of individuals prescribed methadone at a dose of at least 60 mg daily using data from three community-recruited prospective cohort studies of people who use drugs in Vancouver, Canada from December 2016 through March 2020.
Keywords
Advocacy
About PWUD
Illegal drugs
Opioids
Peer/PWLLE program involvement
Substitution/OAT
Withdrawal
