Polysubstance Use and Post-Discharge Mortality Risk Among Hospitalized Patients with Opioid Use Disorder

Original research
by
Hochstatter, Karli R. et al

Release Date

2023

Geography

USA

Language of Resource

English

Full Text Available

Yes

Open Access / OK to Reproduce

Yes

Peer Reviewed

Yes

Objective

This study aimed to examine the association of comorbid cocaine, alcohol (binge drinking), and sedative use with mortality among hospitalized patients with opioid use disorder (OUD).

Findings/Key points

There is a high risk of post-discharge mortality among hospitalized patients with opioid use disorder. Hospitalized patients with opioid use disorder who co-use sedatives are at a significantly increased risk of all-cause mortality post-discharge. Hospitalized patients with opioid use disorder who have less than a high school education are at a significantly increased risk of all-cause mortality and drug overdose death post-discharge.

Design/methods

A subsample of adult medical/surgical hospital patients with OUD who were seen by a hospital addiction consultation service in Baltimore City and enrolled in a randomized trial of a patient navigation intervention were included in this study (N=314). Death certificate data from the Maryland Division of Vital Records was used, covering 3.3-5.5 years post-discharge.

Keywords

Mortality
Hospitals
About PWUD
Outcomes
Transitions in care/treatment