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Full Text Available
Open Access / OK to Reproduce
Peer Reviewed
Objective
While several case studies have indicated that opioid-related ODs can result in cognitive impairment, the possible association has not yet been systematically investigated.
Findings/Key points
Findings revealed that opioid-related ODs may be associated with, or contribute to, reduced cognition. Extent of the impairment appears contingent upon individuals’ premorbid intellectual functioning and the cumulative number of past ODs. While statistically significant, clinical significance may be limited given that performance differences (~4 – 8 points) were not particularly robust.
Direct link if DOI is not yet activated: https://www.sciencedirect.com/science/article/abs/pii/S0376871623001035
Design/methods
78 participants with a history of OUD who reported experiencing an OD in the past year (n=35) or denied a lifetime history of OD (n=43) completed this study.
