A Pilot Study Investigating Cognitive Impairment Associated with Opioid Overdose

Original research
par
Mahoney, James J. III et al

Date de publication

2023

Géographie

USA

Langue de la ressource

English

Texte disponible en version intégrale

Non

Open Access / OK to Reproduce

Non

Évalué par des pairs

Yes

L’objectif

While several case studies have indicated that opioid-related ODs can result in cognitive impairment, the possible association has not yet been systematically investigated.

Constatations/points à retenir

Findings revealed that opioid-related ODs may be associated with, or contribute to, reduced cognition. Extent of the impairment appears contingent upon individuals’ premorbid intellectual functioning and the cumulative number of past ODs. While statistically significant, clinical significance may be limited given that performance differences (~4 – 8 points) were not particularly robust.

Direct link if DOI is not yet activated: https://www.sciencedirect.com/science/article/abs/pii/S0376871623001035

La conception ou méthodologie de recherche

78 participants with a history of OUD who reported experiencing an OD in the past year (n=35) or denied a lifetime history of OD (n=43) completed this study.

Mots clés

Overdose
About PWUD
Mental health