Original research
by
Darwish, Mona & Fang Xie
Release Date
2012
Geography
USA
Language of Resource
English
Full Text Available
No
Open Access / OK to Reproduce
No
Peer Reviewed
Yes
Objective
This analysis provides an overview of the pharmacokinetic profile of FBT based on pooled data from nine pharmacokinetic studies.
Findings/Key points
Based on the individual studies, bioequivalence was shown for sublingual and buccal tablet placement, and no significant effect of dwell time (duration of FBT presence in the oral cavity) was observed. The pharmacokinetic profile of FBT was characterized by rapid absorption, which is consistent with the rapid-onset efficacy profile of FBT observed in clinical studies.
Design/methods
Pooled data from nine studies, total n=365
Keywords
About prescribers
Chronic pain
