Original research
par
Darwish, Mona & Fang Xie
Date de publication
2012
Géographie
USA
Langue de la ressource
English
Texte disponible en version intégrale
Non
Open Access / OK to Reproduce
Non
Évalué par des pairs
Yes
L’objectif
This analysis provides an overview of the pharmacokinetic profile of FBT based on pooled data from nine pharmacokinetic studies.
Constatations/points à retenir
Based on the individual studies, bioequivalence was shown for sublingual and buccal tablet placement, and no significant effect of dwell time (duration of FBT presence in the oral cavity) was observed. The pharmacokinetic profile of FBT was characterized by rapid absorption, which is consistent with the rapid-onset efficacy profile of FBT observed in clinical studies.
La conception ou méthodologie de recherche
Pooled data from nine studies, total n=365
Mots clés
About prescribers
Chronic pain
