Original research
by
Hser, Yih-Ing et al
Release Date
2021
Geography
USA
Language of Resource
English
Full Text Available
No
Open Access / OK to Reproduce
No
Peer Reviewed
Yes
Objective
To investigate whether reduction in opioid use differs when treated by either buprenorphine–naloxone (BUP) or methadone (MET) among adults with comorbid opioid use disorder (OUD) and mental disorders.
Findings/Key points
Among adults with comorbid opioid use disorder and mental disorders, treatment with buprenorphine–naloxone produced greater reductions in opioid use than treatment with methadone.
Design/methods
In a randomized controlled trial, adults with OUD were randomized to 24 weeks of either BUP or MET treatment and were followed up in 3-yearly assessments (n=597)
Keywords
About prescribers
Outcomes
Illegal drugs
Substitution/OAT
Mental health
