Long-term follow-up assessment of opioid use outcomes among individuals with comorbid mental disorders and opioid use disorder treated with buprenorphine or methadone in a randomized clinical trial

Original research
par
Hser, Yih-Ing et al

Date de publication

2021

Géographie

USA

Langue de la ressource

English

Texte disponible en version intégrale

Non

Open Access / OK to Reproduce

Non

Évalué par des pairs

Yes

L’objectif

To investigate whether reduction in opioid use differs when treated by either buprenorphine–naloxone (BUP) or methadone (MET) among adults with comorbid opioid use disorder (OUD) and mental disorders.

Constatations/points à retenir

Among adults with comorbid opioid use disorder and mental disorders, treatment with buprenorphine–naloxone produced greater reductions in opioid use than treatment with methadone.

La conception ou méthodologie de recherche

In a randomized controlled trial, adults with OUD were randomized to 24 weeks of either BUP or MET treatment and were followed up in 3-yearly assessments (n=597)

Mots clés

About prescribers
Outcomes
Illegal drugs
Substitution/OAT
Mental health