Original research
par
Hser, Yih-Ing et al
Date de publication
2021
Géographie
USA
Langue de la ressource
English
Texte disponible en version intégrale
Non
Open Access / OK to Reproduce
Non
Évalué par des pairs
Yes
L’objectif
To investigate whether reduction in opioid use differs when treated by either buprenorphine–naloxone (BUP) or methadone (MET) among adults with comorbid opioid use disorder (OUD) and mental disorders.
Constatations/points à retenir
Among adults with comorbid opioid use disorder and mental disorders, treatment with buprenorphine–naloxone produced greater reductions in opioid use than treatment with methadone.
La conception ou méthodologie de recherche
In a randomized controlled trial, adults with OUD were randomized to 24 weeks of either BUP or MET treatment and were followed up in 3-yearly assessments (n=597)
Mots clés
About prescribers
Outcomes
Illegal drugs
Substitution/OAT
Mental health