Original research
by
Padhan, Milan et al
Release Date
2023
Geography
International
Language of Resource
English
Full Text Available
No
Open Access / OK to Reproduce
No
Peer Reviewed
Yes
Objective
The present meta-analysis was conducted to evaluate the efficacy and safety of tramadol in the treatment of opioid withdrawal.
Findings/Key points
Authors conclude that the efficacy of tramadol in reducing opioid withdrawal symptoms is not significantly different from comparators with low certainty of evidence against placebo, moderate against methadone, whereas with high certainty of evidence against buprenorphine and clonidine.
Design/methods
Data from eight relevant clinical trials
Keywords
Withdrawal
Clinical guidance