Efficacy and safety of tramadol in the treatment of opioid withdrawal: A meta-analysis of randomized controlled trials

Original research
par
Padhan, Milan et al

Date de publication

2023

Géographie

International

Langue de la ressource

English

Texte disponible en version intégrale

Non

Open Access / OK to Reproduce

Non

Évalué par des pairs

Yes

L’objectif

The present meta-analysis was conducted to evaluate the efficacy and safety of tramadol in the treatment of opioid withdrawal.

Constatations/points à retenir

Authors conclude that the efficacy of tramadol in reducing opioid withdrawal symptoms is not significantly different from comparators with low certainty of evidence against placebo, moderate against methadone, whereas with high certainty of evidence against buprenorphine and clonidine.

La conception ou méthodologie de recherche

Data from eight relevant clinical trials

Mots clés

Withdrawal
Clinical guidance