Toxicology and prescribed medication histories among people experiencing fatal illicit drug overdose in British Columbia, Canada

Original research
by
Crabtree, Alexis et al

Release Date

2020

Geography

Canada

Language of Resource

English

Full Text Available

Yes

Open Access / OK to Reproduce

No

Peer Reviewed

Yes

Objective

Our objective was to assess prescription history in the context of postmortem toxicology among people who had a fatal illicit drug overdose in BC.

Findings/Key points

Our data show a high prevalence of nonprescribed fentanyl and stimulants, and a low prevalence of prescribed opioids detected on toxicology in people who died from illicit drug overdose. These results suggest that strategies to address the current overdose crisis in Canada must do much more than target deprescribing of opioids.

Design/methods

Toxicology results from drug overdose deaths involving 1 or more illicit drugs (n=2872), as identified by the BC Coroners Service in 2015–2017, were linked to the prescription drug histories of individuals. Substances identified in toxicology were considered prescribed if the individual had an active dispensation for a matching medication within 60 days before overdose.

Keywords

Overdose
Mortality
Evidence base
Safer supply
Outcomes
Illegal drugs
Stimulants