There is no causality in the "gateway hypothesis": Another test gone amiss

Letter
by
Vanyukov, Michael M.

Release Date

2021

Geography

USA

Language of Resource

English

Full Text Available

Yes

Open Access / OK to Reproduce

No

Peer Reviewed

Yes

Objective

This letter responds to the article by Reed et al. [1]. As indicated in its title, the study used "Mendelian randomization to explore the gateway hypothesis." There are reasons, however, why it failed to, and could not, reach its stated goal.

Findings/Key points

The GH is merely an observation of a temporal order that is frequently found in the US population (but not, for instance, in Japan)

Keywords

Evidence base