Relative effectiveness of medications for opioid-related disorders: A systematic review and network meta-analysis of randomized controlled trials

Lit review
by
Lim, Jihoon et al

Release Date

2022

Geography

International

Language of Resource

English

Full Text Available

Yes

Open Access / OK to Reproduce

Yes

Peer Reviewed

Yes

Objective

Our objective was to unify findings from different healthcare practices and generate evidence to strengthen clinical treatment protocols for the most widely prescribed medications for opioid-use disorders.

Findings/Key points

Methadone was the highest ranked intervention (Surface Under the Cumulative Ranking in the network with control being the lowest. Methadone was superior to buprenorphine for treatment retention and buprenorphine superior to naltrexone.

Design/methods

Meta-analysis

Keywords

Substitution/OAT