Real-world effectiveness of pharmacological treatments of opioid use disorder in a national cohort

Original research
by
Heikkinen, Milja et al

Release Date

2022

Geography

Sweden

Language of Resource

English

Full Text Available

No

Open Access / OK to Reproduce

No

Peer Reviewed

Yes

Objective

To investigate the real-world effectiveness of pharmacological treatments (buprenorphine, methadone) of opioid use disorder (OUD).

Findings/Key points

The use of buprenorphine and methadone are both associated with a significantly lower risk of hospitalization due to opioid use disorder and death due to all and external causes, when compared with non-use.

Design/methods

A nationwide, register-based cohort study - All residents aged 16–64 living in Sweden using OUD-medication from July 2005 to December 2016 (n=5757, 71.8% men).

Keywords

Mortality
Harm reduction
About PWUD
Outcomes
Substitution/OAT