Prescription Opioid Dose Change Before Fatal Opioid-Detected Overdose

Original research
by
Kazemitabar, Maryam et al

Release Date

2024

Geography

USA

Language of Resource

English

Full Text Available

No

Open Access / OK to Reproduce

No

Peer Reviewed

Yes

Objective

This study investigated patterns of prescription opioids dispensed in the 12 months before opioid-detected overdose death in Connecticut between May 8, 2016, and January 2, 2018, considering differences by demographic characteristics.

Findings/Key points

Rapid dose increases in dispensed opioids may be associated with opioid-detected overdose deaths, especially among women.

Design/methods

The sample included decedents who had an opioid dispensed within 30 days preceding death. Using multilevel modeling, we estimated the slope of change in mean morphine equivalent (MME) daily dose over 12 months before death, considering linear and quadratic effects of time.

Keywords

About PWUD
Illegal drugs
Mortality
Opioids
Outcomes
Overdose
Sex/Gender