Predictors of future overdose among people who inject drugs in Baltimore, Maryland

Original research
by
Ramirez, Michael P. et al

Release Date

2024

Geography

USA

Language of Resource

English

Full Text Available

Yes

Open Access / OK to Reproduce

Yes

Peer Reviewed

Yes

Objective

In the US context of an unprecedented magnitude of drug overdose deaths and during the fentanyl era, it becomes increasingly imperative to identify longitudinal predictors to inform targeted prevention planning to effectively reduce overdose among those at highest risk, people who inject drugs (PWID).

Findings/Key points

Overdose during follow-up was positively associated with overdose in the 6 months prior to baseline and more than 6 months prior to baseline versus no prior overdose. Overdose during follow-up was also positively associated with buprenorphine treatment and negatively associated with non-prescribed methadone at baseline. 

Design/methods

The Integrating Services to Improve Treatment and Engagement (INSITE) study followed 720 PWID between June 2018 and August 2019 to evaluate the delivery of mobilized healthcare services in Baltimore, Maryland. The present analyses used logistic regression to identify baseline characteristics predictive of non-fatal or fatal overdose during the 6-month follow-up among 507 participants with overdose information.

Keywords

About PWUD
Hospitals
Injecting drugs
Naloxone
Overdose
Substitution/OAT