Opioid Use Disorder Treatments: An Evidence Map

Original research
by
Sugarman, Allison et al

Release Date

2022

Geography

International

Language of Resource

English

Full Text Available

No

Open Access / OK to Reproduce

No

Peer Reviewed

Yes

Objective

Our aim was to publish an interactive summary of all peer-reviewed interventional and observational trials assessing the treatment of OUD and common clinical outcomes.

Findings/Key points

The most studied OUD interventions were methadone (n=754 studies), buprenorphine (n=499), and naltrexone (n=134). Common treatment outcomes were rates of heroin/opioid use (n=708), treatment retention (n=557), and non-opioid drug use (n=368). Clear gaps included mobile health interventions, studies of OUD treatments in criminal justice settings, and overdose as a clinical outcome.

Design/methods

Lit review (1591 studies included in the map)

Keywords

Substitution/OAT
Evidence base