Opioid treatment program and community pharmacy collaboration for methadone maintenance treatment: results from a feasibility clinical trial

Original research
by
Wu, Li-Tzy et al

Release Date

2022

Geography

USA

Language of Resource

English

Full Text Available

No

Open Access / OK to Reproduce

No

Peer Reviewed

Yes

Objective

Pharmacy administration and dispensing of methadone for methadone maintenance treatment (MMT) can expand treatment access for opioid use disorder (OUD). This study investigated the feasibility and acceptability of a novel model permitting an opioid treatment program (OTP) physician to prescribe methadone for OUD treatment through collaboration with a partnered pharmacy.

Findings/Key points

Of 29 patients eligible at pre-screen, 20 patients (69%) enrolled into the study. Recruitment occurred from 6 August 2020 to 10 October 2020. Treatment retention rate at month 3 was 80% (16 of 20). Two participants returned early to the OTP because of a work/schedule change, one due to pregnancy and one following a non-study-related hospitalization. Medication adherence among 16 patients who were retained was 100%. Intervention fidelity was 100%. All participants attended random call-back visits. None showed evidence of tampering/diversion of methadone. Pharmacists checked the PDMP at all visits. All participants attended psychosocial counseling as planned. There were no positive urine screens for illicit opioid use and no study-related adverse events. All participants endorsed ‘pharmacy is the right location for receiving methadone for MMT’, 88% endorsed ‘convenient or very convenient to receive methadone at the pharmacy’ and 88% were satisfied or very satisfied with the quality of treatment offered.

Design/methods

One OTP physician, two pharmacists and 20 MMT patients receiving between six and 13 take-home methadone doses at 5–160 mg/day

Keywords

About pharmacists
About PWUD
Outcomes
Substitution/OAT
Diversion
Carries/take-home doses