Original research
by
Lier, Audun J. et al
Release Date
2022
Geography
USA
Language of Resource
English
Full Text Available
No
Open Access / OK to Reproduce
No
Peer Reviewed
Yes
Objective
Opioid use disorder (OUD) and injection drug use (IDU) place justice-involved individuals at increased risk for acquiring or transmitting HIV or hepatitis C virus (HCV). Methadone and buprenorphine have been associated with reduced opioid IDU; however, the effect of extended-release naltrexone (XR-NTX) on this behavior is incompletely studied.
Findings/Key points
Injection opioid use was low during incarceration and remained low postrelease in this justice-involved population. Retention on XR-NTX was associated with reduced intravenous opioid use, which has important implications for reducing transmission of HIV and HCV.
Design/methods
Double-blind placebo-controlled trial (n=88)
Keywords
Legal system/law enforcement
Substitution/OAT
