Impact of policy changes and drug shortages on acamprosate and naltrexone use in Ontario, Canada

Original research
by
Konstantelos, Natalia et al

Release Date

2023

Geography

Canada

Language of Resource

English

Full Text Available

No

Open Access / OK to Reproduce

No

Peer Reviewed

Yes

Objective

Acamprosate and naltrexone, evidence-based pharmacotherapies for alcohol use disorder (AUD), are publicly covered by the Ontario Drug Benefit (ODB) programs; however, their availability has changed over time, with expanded formulary access in July 2018, followed by an acamprosate shortage in February 2019 and ending in July 2020. We evaluated the impact of these events on the use of these medications in Ontario, Canada.

Findings/Key points

Although coverage expansion increased access to medications that treat AUD, the shortage of acamprosate led to large reductions in its use, with no responsive increase in naltrexone prescribing.

Design/methods

Time-series analysis (n=10,637)

Keywords

Policy/Regulatory
About prescribers
Outcomes