Original research
by
Gomes, Tara et al
Release Date
2022
Geography
Canada
Language of Resource
English
Full Text Available
Yes
Open Access / OK to Reproduce
Yes
Peer Reviewed
Yes
Objective
To characterize comparative risks and benefits of methadone versus buprenorphine/naloxone in a contemporary cohort where the unregulated drug supply is dominated by fentanyl.
Findings/Key points
Although treatment retention is higher among methadone recipients, overdose risk is also elevated compared to buprenorphine recipients. These findings demonstrate the benefits of any OAT on avoidance of overdose, particularly following treatment discontinuation and with the increasingly unpredictable drug supply in North America.
Design/methods
7517 people initiating buprenorphine were matched to an equal number of methadone-treated individuals
Keywords
Substitution/OAT
Overdose
Illegal drugs
About PWUD
Outcomes
