Original research
by
Nataraj, Nisha et al
Release Date
2022
Geography
USA
Language of Resource
English
Full Text Available
No
Open Access / OK to Reproduce
No
Peer Reviewed
Yes
Objective
To examine potentially unsafe tapering and discontinuation among dosage changes in opioid prescriptions dispensed to US patients on high-dose long-term opioid therapy.
Findings/Key points
Half of patients on high-dose long-term opioid therapy had daily dosages tapered. Many patients experienced dosage reductions exceeding recommended rates. Rapid tapers were more likely among patients with baseline daily dosages ≥150 MME.
Design/methods
Longitudinal observational study (n=595,078)
Keywords
About PWUD
Withdrawal
