Does childhood adversity alter opioid drug reward? A conceptual replication in outpatients before surgery

Original research
by
Carlyle, Molly et al

Release Date

2023

Geography

Norway

Language of Resource

English

Full Text Available

No

Open Access / OK to Reproduce

No

Peer Reviewed

Yes

Objective

We tested whether childhood adversity increased opioid reward, operationalized as drug-induced feeling good and drug liking, in outpatients receiving opioids on the operating table.

Findings/Key points

Ratings of feeling good and drug liking of medically prescribed opioids given before surgery were not higher after childhood adversity, and previous findings were not conceptually replicated.

Design/methods

Observational study (n=151)

Keywords

Chronic pain
Hospitals