Original research
by
Iacono, Anita et al
Release Date
2023
Geography
Canada
Language of Resource
English
Full Text Available
Yes
Open Access / OK to Reproduce
Yes
Peer Reviewed
Yes
Objective
Our aim was to examine uptake, characteristics, treatment patterns and retention of individuals initiating extended-release subcutaneous buprenorphine (BUP-ER), a monthly injectable opioid agonist treatment (OAT).
Findings/Key points
On average, people initiating BUP-ER discontinue within the first 6 months of treatment. While BUP-ER is likely providing an important OAT option, the high occurrence of discontinuation, supplementation with buprenorphine/naloxone, and frequent dose increases suggest inadequacy of current dosing recommendations among a proportion of individuals.
Design/methods
Population-based cohort study (n=2,366)
Keywords
About PWUD
Substitution/OAT
Outcomes
Transitions in care/treatment
