Release Date
Geography
Language of Resource
Full Text Available
Open Access / OK to Reproduce
Peer Reviewed
Objective
Has reliance on abstinence-based treatment outcomes failed to capture the full continuum of treatment response to buprenorphine plus medical counseling (BUP+MC) for opioid use disorder (OUD)?
Findings/Key points
Of the study participants, only 377 patients (43%) would have been labeled a treatment success using an abstinence-based success rule. However, on average, patients labeled as unsuccessful reported substantial decreases in illegal opioid use from a mean of 6.29 days per week pretreatment to 1.51 days per week by week 12.
Design/methods
This study is a secondary data analysis of 4 harmonized randomized clinical trials on BUP+MC for OUD from multiple sites that included 869 patients with OUD.