Capturing the Full Range of Buprenorphine Treatment Response

Original research
by
Bailey, Allen J. et al

Release Date

2024

Geography

USA

Language of Resource

English

Full Text Available

No

Open Access / OK to Reproduce

No

Peer Reviewed

Yes

Objective

Has reliance on abstinence-based treatment outcomes failed to capture the full continuum of treatment response to buprenorphine plus medical counseling (BUP+MC) for opioid use disorder (OUD)?

Findings/Key points

Of the study participants, only 377 patients (43%) would have been labeled a treatment success using an abstinence-based success rule. However, on average, patients labeled as unsuccessful reported substantial decreases in illegal opioid use from a mean of 6.29 days per week pretreatment to 1.51 days per week by week 12.

Design/methods

This study is a secondary data analysis of 4 harmonized randomized clinical trials on BUP+MC for OUD from multiple sites that included 869 patients with OUD.

Keywords

About PWUD
Illegal drugs
Mental health
Opioids
Return to use
Substitution/OAT
Treatment/recovery