Brief Report: A population-based study of the impact of the COVID-19 pandemic on benzodiazepine use among children and young adults

Report
by
Antoniou, Tony et al

Release Date

2024

Geography

Canada

Language of Resource

English

Full Text Available

Yes

Open Access / OK to Reproduce

Yes

Peer Reviewed

Yes

Objective

The COVID-19 pandemic was associated with increases in the prevalence of depression and anxiety among children and young adults. This study aims to determine whether the pandemic was associated with changes in prescription benzodiazepine use. 

Findings/Key points

An immediate decline in benzodiazepine dispensing was found. Lower than expected benzodiazepine dispensing rates were observed each month of the pandemic from April 2020 onward, with relative percent differences ranging from − 7.4% (95% CI: -10.1% to – 4.7%) to -20.9% (95% CI: -23.2% to -18.6%). Results were generally similar in analyses stratified by sex, age, neighbourhood income quintile, and urban versus rural residence.

Design/methods

A population-based study of benzodiazepine dispensing to children and young adults ≤ 24 years old between January 1, 2013, and June 30, 2022 was conducted. Structural break analyses was used to identify the pandemic month(s) when changes in prescription benzodiazepine dispensing occurred, and interrupted time series models to quantify changes in dispensing following the structural break and compare observed and expected benzodiazepine use. 

Keywords

Benzodiazepines
Evidence base
Hesitancy of prescribers
Mental health
Youth