Associations between naloxone prescribing and opioid overdose among patients with acute and chronic pain conditions

Original research
by
Qeadan, Fares & Erin Fanning Madden

Release Date

2022

Geography

USA

Language of Resource

English

Full Text Available

Yes

Open Access / OK to Reproduce

Yes

Peer Reviewed

Yes

Objective

To assess whether naloxone prescribing in clinical contexts targeted pain patients most at risk for opioid overdose.

Findings/Key points

Receiving a naloxone prescription appears to be associated with increased risk of subsequent opioid overdose among patients with acute and chronic pain, suggesting prescribers often identify patients most in need of naloxone.

Design/methods

Three patient groups were followed for 2 years during 2009 to 2017: individuals with shoulder or long bone fractures (n = 252 424), chronic pain syndrome (CPS) (n = 76 141), or non-traumatic low back pain (n = 792 956) who received an opioid prescription.

Keywords

Overdose
Mortality
Harm reduction
About prescribers
Outcomes
Chronic pain