The Association of Prescribed Opioids and Incident Cardiovascular Disease

Original research
by
Sung, Minhee L. et al

Release Date

2024

Geography

USA

Language of Resource

English

Full Text Available

No

Open Access / OK to Reproduce

No

Peer Reviewed

Yes

Objective

We determined the association between prescribed opioid receipt with incident cardiovascular disease (CVD).

Findings/Key points

Prevalence of hypertension, diabetes, current smoking, alcohol and cocaine use disorder, and depression was higher in patients receiving opioids versus those not but were well-balanced by matching weights. Unadjusted CVD incidence rates per 1,000-person-years were higher among those receiving opioids versus those not: 17.4 versus 14.7. In adjusted analyses, those receiving opioids versus those not had an increased hazard of incident CVD.

Design/methods

Data from the Veterans Aging Cohort Study, a national prospective cohort of Veterans with/without Human Immunodeficiency Virus (HIV) receiving Veterans Health Administration care.

Keywords

Chronic pain
Outcomes