Resources

Welcome to our searchable resource and literature collection on safer supply and related topics.

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Mutual-Help Group Participation for Substance Use Problems in the US: Correlates and Trends from 2002-2018

Mutual-help groups (MHGs) are an integral component of the substance use disorder (SUD) treatment system in the U.S., and growing evidence suggests that they are effective and cost-effective for SUD-r
Original research | 2021
Wrap-around services, Equity, About PWUD, Poverty, Sex/Gender

Real-world effectiveness of pharmacological treatments of opioid use disorder in a national cohort

To investigate the real-world effectiveness of pharmacological treatments (buprenorphine, methadone) of opioid use disorder (OUD).
Original research | 2022
Mortality, Harm reduction, About PWUD, Outcomes, Substitution/OAT

Sex-based differences in psychiatric symptoms and opioid abstinence during buprenorphine/naloxone treatment in adolescents with opioid use disorders

In the current study, we examined sex-based differences in psychiatric symptoms and relationships among sex, psychiatric symptoms, and opioid use outcomes in youth with OUD receiving buprenorphine/nal
Original research | 2022
About PWUD, Outcomes, Illegal drugs, Youth, Substitution/OAT, Sex/Gender , Mental health

Topiramate for the Treatment of Cocaine Addiction: A Randomized Clinical Trial

To determine the efficacy of topiramate vs placebo as a treatment for cocaine dependence.

Original research | 2013
Stimulants, Substitution/OAT

Treatment access for opioid use disorder in pregnancy among rural and American Indian communities

Opioid use disorder (OUD) in pregnancy disproportionately impacts rural and American Indian (AI) communities.

Original research | 2021
About prescribers, Barriers and enablers, Indigenous, Rural/remote, Substitution/OAT, Sex/Gender , Parents/caregivers

Treatment Approaches for Users of Methamphetamine: A Practical Guide for Frontline Workers

Alcohol and other drug (AOD) workers from a variety of service settings are now frequently required to respond to methamphetamine users who are experiencing the harmful effects of methamphetamine, goi
Guide or handbook | 2008
Clinical guidance, Harm reduction, About prescribers, Social services, Illegal drugs, Stimulants, Transitions in care/treatment

Treatment preference for opioid use disorder among people who are incarcerated

Currently, three classes (opioid agonist, partial agonist-antagonist, and antagonist) of FDA-approved medications for opioid use disorder (MOUD) exist, yet few correctional settings offer any medicati
Original research | 2021
About PWUD, Legal system/law enforcement, Substitution/OAT, Stigma

“It’s called overamping”: experiences of overdose among people who use methamphetamine

We explore qualitative narratives of methamphetamine overdose and strategies used by people who use drugs to reduce the undesirable effects associated with methamphetamine use.
Original research | 2022
Overdose, Harm reduction, About PWUD, Illegal drugs, Stimulants

“It’s probably going to save my life;” Attitudes towards treatment among people incarcerated in the era of fentanyl

Little is known about knowledge and perceptions of fentanyl among people who are incarcerated.
Original research | 2022
Overdose, Harm reduction, Safer supply, About PWUD, Legal system/law enforcement, Illegal drugs, Substitution/OAT

“Nothing about us, without us”: Negotiating the personal and professional as activists and academics who use drugs

Commentary | 2021
Advocacy, About PWUD, Illegal drugs, Workplace, Peer/PWLLE program involvement

A qualitative study on pharmacy policies toward over-the-counter syringe sales in a rural epicenter of US drug-related epidemics

While pharmacies have potential to be an easily accessible source of sterile syringes, research in cities has identified moral, legal and ethical barriers that preclude over-the-counter (OTC) sales to
Original research | 2022
Harm reduction, Hesitancy of prescribers , About pharmacists, Rural/remote, Stigma

Associations between mental illness and non-medical use of prescription opioids among a sample of people who use drugs in Australia and New Zealand

We investigated the associations between nonmedical use of prescription opioids (NUPO), mental illnesses, and other substance use.
Original research | 2022
About PWUD, Illegal drugs, Diversion, Mental health

Factors associated with opioid-involved overdose among previously incarcerated people in the U.S.: A community engaged narrative review

Research to identify risk and protective factors for overdose is often conducted using administrative data or researcher-derived surveys and without explicit input from people with lived experience.
Lit review | 2021
Overdose, About PWUD, Legal system/law enforcement, Illegal drugs, Peer/PWLLE program involvement

Injection of Opioid Tablets: Risks and Harm Reduction Information Summary

Report | 2019
Harm reduction, Injecting drugs, Safer supply

Intermediate Stable States in Substance Use

We empirically examine the stability of and transitions between three substance use states: zero-use, moderate use, and heavy use.
Original research | 2022
Evidence base, About PWUD, Illegal drugs

Investigating opioid preference to inform safe supply services: A cross sectional study

This study aims to identify opioid preferences and associated variables to inform further phases of safe supply program implementation.
Original research | 2022
Safer supply, About PWUD, Housing, Illegal drugs, Indigenous, Rural/remote, Small/medium cities, Sex/Gender , SCS/OPS

Key considerations for the implementation of clinically focused Prescription Drug Monitoring Programs to avoid unintended consequences

Commentary | 2022
Policy/Regulatory, Hesitancy of prescribers , About pharmacists, About prescribers, Barriers and enablers

Opioid abuse and austerity: Evidence on health service use and mortality in England

We examine the impact of spending cuts resulting from government prescribed austerity measures on opioid-related hospitalisations and mortality, thereby expanding on existing evidence suggesting a cou
Original research | 2021
Overdose, Mortality, Harm reduction, Policy/Regulatory, Illegal drugs

Patterns of Medication and Healthcare Use among People who Died of an Opioid-Related Toxicity during the COVID-19 Pandemic in Ontario

Report | 2022
Overdose, Mortality, Evidence base, About PWUD, Outcomes, Housing, Illegal drugs, Stimulants, Substitution/OAT, Mental health

Peer Engagement Best Practices: A Guide for Health Authorities and other providers

Peer engagement is essential to better understand local risk environments, including issues related to physical, social, and political environments.
Guide or handbook | 2017
Advocacy, About PWUD, Barriers and enablers, Peer/PWLLE program involvement, Stigma

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