Buprenorphine/Naloxone vs Methadone for the Treatment of Opioid Use Disorder

Original research
par
Nosyk, B. et al

Date de publication

2024

Géographie

Canada

Langue de la ressource

English

Texte disponible en version intégrale

Non

Open Access / OK to Reproduce

Non

Évalué par des pairs

Yes

L’objectif

To assess the risk of treatment discontinuation and mortality among individuals receiving buprenorphine/naloxone vs methadone for the treatment of opioid use disorder.

Constatations/points à retenir

Individuals receiving methadone had a lower risk of treatment discontinuation compared with those who received buprenorphine/naloxone. The risk of mortality while receiving treatment was similar between medications.

La conception ou méthodologie de recherche

Population-based retrospective cohort study using linked health administrative databases in British Columbia, Canada. The study included treatment recipients between January 1, 2010, and March 17, 2020, who were 18 years or older and not incarcerated, pregnant, or receiving palliative cancer care at initiation.

Mots clés

About PWUD
Clinical guidance
Mortality
Opioids
Outcomes
Substitution/OAT
Treatment/recovery