Low-Dose Initiations of Buprenorphine in the Fentanyl Era—A Search for Evidence-Based Approaches to an Evolving Crisis

Commentary
par
Berk, J., Rose, M., & Thakar, A. P.

Date de publication

2025

Géographie

USA

Langue de la ressource

English

Texte disponible en version intégrale

Oui

Open Access / OK to Reproduce

Oui

Évalué par des pairs

Yes

L’objectif

This commentary is concerned with buprenorphine treatment for individuals with opioid use disorder in the fentanyl era. Despite changes in policy USA-wide that has increased the accessibility of buprenorphine, mitigating precipitated withdrawal during initiation is more of a challenge. There is a lack of clinical guidelines and best practises in area.

Constatations/points à retenir

In order to address the needs of this population, the authors highlight next research steps that need to be undertaken to advance in this field. Namely: prioritizing clinical trials, new approaches to research design, the need to categorize risk factors and exploring cotreatment of stimulant use disorder alongside opioid use treatment.

Mots clés

Barriers and enablers
Illegal drugs
Overdose
Policy/Regulatory
Stimulants
Substitution/OAT
Withdrawal
Treatment/recovery