Original research
par
Bakouni, Hamzah et al
Date de publication
2023
Géographie
Canada
Langue de la ressource
English
Texte disponible en version intégrale
Non
Open Access / OK to Reproduce
Non
Évalué par des pairs
Yes
L’objectif
We aimed to assess the effect of methadone on non-opioid substance use compared to buprenorphine/naloxone (BUP/NX), to explore whether non-opioid substance use is associated with opioid use and retention in treatment, and to test non-opioid use as a moderator of associations between methadone with retention in opioid agonist treatment (OAT) and opioid use compared to BUP/NX.
Constatations/points à retenir
Methadone did not show a significant effect on overall non-opioid substance use in POUD compared to BUP/NX treatment but was associated with lower odds of benzodiazepine and THC use in particular. Non-opioid substance use did not predict OAT outcomes.
La conception ou méthodologie de recherche
Secondary analysis of data from the OPTIMA trial
Mots clés
Substitution/OAT
