The Impact of Longitudinal Substance Use Patterns on the Risk of Opioid Agonist Therapy Discontinuation: A Repeated Measures Latent Class Analysis

Original research
par
Cui, Zishan et al

Date de publication

2023

Géographie

Canada

Langue de la ressource

English

Texte disponible en version intégrale

Oui

Open Access / OK to Reproduce

Oui

Évalué par des pairs

Yes

L’objectif

Our study aimed to characterize longitudinal substance use patterns among people receiving OAT and evaluate the association between different substance use patterns and the risk of OAT discontinuation.

Constatations/points à retenir

We found that compared to the primarily crack use class, the two opioid and stimulant use classes carried a higher risk of OAT discontinuation, while the primarily cannabis and crack use class had a lower OAT discontinuation risk. Our findings highlight the need for integrated treatment strategies to manage the co-use of opioids and stimulants during receipt of OAT and suggest future research should explore the potential of cannabis as a harm reduction strategy or adjunctive treatment to OAT.

La conception ou méthodologie de recherche

Data were collected from two prospective cohorts between 2005 and 2020 in Vancouver, Canada.

Mots clés

About PWUD
Illegal drugs
Stimulants
Substitution/OAT