Original research
par
Larochelle, Marc R. et al
Date de publication
2022
Géographie
USA
Langue de la ressource
English
Texte disponible en version intégrale
Oui
Open Access / OK to Reproduce
Non
Évalué par des pairs
Yes
L’objectif
To identify the association of opioid tapering or abrupt discontinuation with opioid overdose and suicide events among patients receiving stable long-term opioid therapy without evidence of opioid misuse.
Constatations/points à retenir
This study identified a small absolute increase in risk of harms associated with opioid tapering compared with a stable opioid dosage. These results do not suggest that policies of mandatory dosage tapering for individuals receiving a stable long-term opioid dosage without evidence of opioid misuse will reduce short-term harm via suicide and overdose.
La conception ou méthodologie de recherche
Trial emulation approach using a large US claims data set of individuals with commercial insurance or Medicare
Mots clés
Substitution/OAT
Transitions in care/treatment
