Duration of use and outcomes among people with opioid use disorder initiating methadone and buprenorphine in Ontario: A population-based propensity-score matched cohort study

Original research
par
Gomes, Tara et al

Date de publication

2022

Géographie

Canada

Langue de la ressource

English

Texte disponible en version intégrale

Non

Open Access / OK to Reproduce

Non

Évalué par des pairs

Yes

L’objectif

To characterize comparative risks and benefits of methadone versus buprenorphine/naloxone in a contemporary cohort where the unregulated drug supply is dominated by fentanyl.

Constatations/points à retenir

Although treatment retention is higher among methadone recipients, overdose risk is also elevated compared to buprenorphine recipients. Overdose rates in the period following OAT discontinuation were higher than those observed while on treatment, but did not differ significantly by OAT type.

La conception ou méthodologie de recherche

Cohort study

Mots clés

Overdose
Substitution/OAT
About PWUD
Outcomes