Original research
par
Krebs, Emanuel et al
Date de publication
2021
Géographie
Canada
Langue de la ressource
English
Texte disponible en version intégrale
Non
Open Access / OK to Reproduce
Non
Évalué par des pairs
Yes
L’objectif
The province of British Columbia, Canada, changed the existing oral anhydrous methadone solution to a 10-times more concentrated pre-mixed solution, Methadose®, on February 1, 2014. We aimed to assess the immediate effects of the methadone reformulation on missed doses, days off methadone, changes in medication dosing and dispensations of opioids for pain, and hospitalizations and mortality among all people receiving treatment at or near the time of the change
Constatations/points à retenir
The regulatory change resulted in increases in treatment discontinuation, more instances of methadone dose increases, and was associated with increased prescriptions of other opioid analgesics.
La conception ou méthodologie de recherche
Population-based retrospective cohort study
Mots clés
Policy/Regulatory
About PWUD
Outcomes
Substitution/OAT
