Original research
par
Johnson, Bankole A. et al
Date de publication
2013
Géographie
USA
Langue de la ressource
English
Texte disponible en version intégrale
Oui
Open Access / OK to Reproduce
Non
Évalué par des pairs
Yes
L’objectif
To determine the efficacy of topiramate vs placebo as a treatment for cocaine dependence.
Constatations/points à retenir
Topiramate is more efficacious than placebo at increasing the mean weekly proportion of cocaine nonuse days and associated measures of clinical improvement among cocaine-dependent individuals.
La conception ou méthodologie de recherche
Double-blind, randomized, placebo-controlled, 12-week trial of 142 cocaine-dependent adults in clinical research facilities at the University of Virginia between November 22, 2005, and July 25, 2011.
Mots clés
Stimulants
Substitution/OAT
