Original research
par
Oviedo-Joekes, Eugenia et al
Date de publication
2009
Géographie
Canada
Langue de la ressource
English
Texte disponible en version intégrale
Oui
Open Access / OK to Reproduce
Non
Évalué par des pairs
Yes
L’objectif
We compared injectable diacetylmorphine with oral methadone maintenance therapy in patients with opioid dependence that was refractory to treatment
Constatations/points à retenir
Injectable diacetylmorphine was more effective than oral methadone. Because of a risk of overdoses and seizures, diacetylmorphine maintenance therapy should be delivered in settings where prompt medical intervention is available.
La conception ou méthodologie de recherche
n=226 randomized to methadone or diacetylmorphine
Mots clés
Evidence base
Policy/Regulatory
Safer supply
About prescribers
Outcomes
Illegal drugs
Substitution/OAT
