Wound-associated agents in the unregulated drug supply: Evidence from a statewide drug checking program

Original research
par
Martin, Emily M. et al

Date de publication

2025

Géographie

USA

Langue de la ressource

English

Texte disponible en version intégrale

Non

Open Access / OK to Reproduce

Non

Évalué par des pairs

Yes

L’objectif

The aim of this paper is to examine known and potential wound-associated agents’ (xylazine, levamisole, medetomidine) prevalence in Maryland's unregulated drug supply.

Constatations/points à retenir

Xylazine was detected in 33.4 % of samples and primarily co-occurred with fentanyl; heroin and related compounds; and other opioids, stimulants, and anesthetics. Xylazine's prevalence decreased over time and varied geographically. Levamisole and medetomidine occurred in 1.9 % and 0.7 % of samples respectively with no significant co-occurrence.

La conception ou méthodologie de recherche

Using data from Maryland's statewide drug checking program, Rapid Analysis of Drugs (RAD), this paper discusses samples that were voluntarily provided at participating syringe service programs and analyzed at the National Institute of Standards and Technology between October 2021 and October 2023 (N= 2,210). We calculated prevalence and chi-square significance to assess co-occurrence of wound-associated agents and other substances and evaluated xylazine's prevalence over time.

Mots clés

Drug checking
Harm reduction
Illegal drugs
Overdose
Xylazine