Date de publication
Géographie
Langue de la ressource
Texte disponible en version intégrale
Open Access / OK to Reproduce
Évalué par des pairs
L’objectif
This study examined whether Illicitly manufactured fentanyl (IMF) use predicts hepatitis C virus (HCV) and human immunodeficiency virus (HIV) incidence among a cohort of people who inject drugs (PWID) in San Diego, California and Tijuana, Mexico.
Constatations/points à retenir
The results document a novel association between IMF and HCV seroconversion among PWID in Tijuana–San Diego. Few HIV seroconversions (n = 10) precluded our ability to assess if a similar relationship held for HIV. IMF's short half-life may destabilize PWID—increasing the need for repeat dosing and sharing smoking materials and syringes.
La conception ou méthodologie de recherche
PWID were recruited during 2020–2022, undergoing semi-annual interviewer-administered surveys and HIV and HCV serological rapid tests through 2024. Cox regression was conducted to examine predictors of seroconversion considering self-reported IMF use as a 6-month lagged, time-dependent covariate.
