Bupropion for treatment of amphetamine-type stimulant use disorder: A systematic review and meta-analysis of placebo-controlled randomized clinical trials

Lit review
par
Bakouni, Hamzah et al

Date de publication

2023

Géographie

International

Langue de la ressource

English

Texte disponible en version intégrale

Non

Open Access / OK to Reproduce

Non

Évalué par des pairs

Yes

L’objectif

This meta-analysis pooled effect estimates of outcomes from placebo-controlled randomized clinical trials (RCTs) examining bupropion efficacy and safety for amphetamine-type stimulant use disorder (ATSUD) treatment.

Constatations/points à retenir

Bupropion showed a significant modest reduction in ATS use and ATS craving (both rated as very low-quality evidence), larger in males (craving), and with longer treatment (ATS use).

La conception ou méthodologie de recherche

Lit review (8 RCTs included)

Mots clés

Stimulants