Opioid analgesia for acute low back pain and neck pain (the OPAL trial): a randomised placebo-controlled trial

Original research
par
Jones, Caitlin M.P. et al

Date de publication

2023

Géographie

Australia

Langue de la ressource

English

Texte disponible en version intégrale

Non

Open Access / OK to Reproduce

Non

Évalué par des pairs

Yes

L’objectif

Opioid analgesics are commonly used for acute low back pain and neck pain, but supporting efficacy data are scarce. We aimed to investigate the efficacy and safety of a judicious short course of an opioid analgesic for acute low back pain and neck pain.

Constatations/points à retenir

Opioids should not be recommended for acute non-specific low back pain or neck pain given that we found no significant difference in pain severity compared with placebo. This finding calls for a change in the frequent use of opioids for these conditions.

La conception ou méthodologie de recherche

Triple-blinded, placebo-controlled randomised trial (n=347)

Mots clés

Chronic pain
Clinical guidance