Comprehensive needle and syringe program and opioid agonist therapy reduce HIV and hepatitis c virus acquisition among people who inject drugs in different settings: A pooled analysis of emulated trials

Original research
par
van Santen, Daniela K. et al

Date de publication

2023

Géographie

International

Langue de la ressource

English

Texte disponible en version intégrale

Oui

Open Access / OK to Reproduce

Oui

Évalué par des pairs

Yes

L’objectif

We measured the pooled effect of needle and syringe program (NSP) and opioid agonist therapy (OAT) participation on HIV and HCV incidence in the Netherlands, Canada and Australia.

Constatations/points à retenir

In the Netherlands, Canada and Australia, comprehensive needle and syringe program and opioid agonist therapy participation appears to substantially reduce HIV and hepatitis C acquisition compared with no or partial needle and syringe program/opioid agonist therapy participation

La conception ou méthodologie de recherche

For each cohort, we emulated the design and statistical analysis of a target trial using observational data

Mots clés

Harm reduction
Substitution/OAT
Wrap-around services
About PWUD