Original research
par
MacDonald, T. et al
Date de publication
2022
Géographie
Australia
Langue de la ressource
English
Texte disponible en version intégrale
Non
Open Access / OK to Reproduce
Non
Évalué par des pairs
Yes
L’objectif
Discontinuation from benzodiazepines can be problematic for patients and may result in a withdrawal syndrome, which can be protracted and last months to years.
Constatations/points à retenir
Self-reported rates of abstinence from benzodiazepines at three months was between 46.2% and 61.5%. Flumazenil may yield greater success than benzodiazepine tapering from high dose (>30 mg diazepam equivalent) benzodiazepine use.
La conception ou méthodologie de recherche
26 participants received low-dose subcutaneous flumazenil infusions (4 mg/24 h for approximately eight days) as part of a randomised control crossover trial.
Mots clés
Clinical guidance
Overdose
Outcomes
