Methylphenidate and the risk of psychosis in adolescents and young adults: a population-based cohort study

Original research
par
Hollis, Chris et al

Date de publication

2019

Géographie

Sweden

Langue de la ressource

English

Texte disponible en version intégrale

Oui

Open Access / OK to Reproduce

Oui

Évalué par des pairs

Yes

L’objectif

We aimed to determine whether the risk of psychotic events increases immediately after initiation of methylphenidate treatment or, in the longer term, 1 year after treatment initiation in adolescents and young adults with and without a previously diagnosed psychotic disorder.

Constatations/points à retenir

Contrary to clinical concerns, we found no evidence that initiation of methylphenidate treatment increases the risk of psychotic events in adolescents and young adults, including in those individuals with a history of psychosis. Our study should reassure clinicians considering initiating methylphenidate treatment for ADHD in adolescents and young adults, and it challenges the widely held view in clinical practice that methylphenidate should be avoided, or its use restricted, in individuals with a history of psychosis.

La conception ou méthodologie de recherche

Cohort study

Mots clés

Stimulants
Youth
Mental health
Transitions in care/treatment
About prescribers
Outcomes