Original research
par
Jones, Wayne, et al
Date de publication
2021
Géographie
Canada
Langue de la ressource
English
Texte disponible en version intégrale
Oui
Open Access / OK to Reproduce
Non
Évalué par des pairs
Yes
L’objectif
The present study examined whether differential provincial reductions in medical opioid dispensing following restrictive regulations (post-2010) were associated with differential contributions of fentanyl to opioid mortality.
Constatations/points à retenir
Provincial reductions in medical opioid dispensing indicated (near-)significant correlations with fentanyl contribution rates to opioid-related death totals. Differential reductions in pharmaceutical opioid availability may have created supply voids for nonmedical use, substituted with synthetic/toxic (e.g., fentanyl) opioids and leading to accelerated opioid mortality. Implications of these possible unintended adverse consequences warrant consideration for public health policy.
La conception ou méthodologie de recherche
Data from a pan-Canadian pharmacy-based dispensing panel
Mots clés
Mortality
Evidence base
Harm reduction
Policy/Regulatory
Hesitancy of prescribers
Advocacy
